DETECTION OF MODIFIED CELLS USING “LAB-ON-A-CHIP (LOC)” MICROFLUIDIC DEVICES

Abstract

Biological medicine is also called “the medicine of the future” because of its performances to detect in time different diseases which the world population is facing. Sometimes, it can be the only chance to survive or to recover. It is wanted to create efficient and precise analytic instruments needed in medical diagnoses. Biochips (lab-on-a-chip systems) are part of the current concerns of the micro-nanobiotechnologies and nanomedicine, both nationally and internationally. Biochips have applicability in medical field, in clinical research due to its complexity and the importance of the information provided for rapid diagnosis and therapy, with implications in lowering the risk of relapse, and due to the reduced costs compared with the current methods.

This paper presents devices that detect, capture or separate different cells using different cell properties (size, surface markers, electric properties, deformability, etc.). In this kind of system, a low-cost sensor is the main piece of interest.